Sedation, analgesia and muscle relaxation in cattle, sheep, goats, dogs and cats.
Cattle. 0.15 to 0.75 mL/100 kg bodyweight by slow intravenous injection or 0.50 to 1.75 mL/100 kg intramuscularly, depending on the degree of sedation required. See literature included with product. Ruminants are the most sensitive of the domestic animals to the action of xylazine. In cattle, dose levels required to produce deep sedation and analgesia are one-tenth those required in horses, dogs and cats.
Mild sedation. Intramuscular (IM) dose: 0.25 mL/50 kg; 0.5 mL/100 kg; 1.25 mL/250 kg; 2.25 mL/450 kg. Intravenous (IV) dose: 0.08 mL/50 kg; 0.15 mL/100 kg; 0.38 mL/250 kg; 0.68 mL/450 kg. With these doses, the animal should remain standing. Suitable for procedures such as clinical examination, transportation, rectal examination, weighing, radiography, bandaging, etc.; as an adjunct to local anaesthesia for standing surgery; as a premedicant for general anaesthesia.
Moderate sedation. IM dose: 0.44 mL/50 kg; 0.9 mL/100 kg; 2.2 mL/250 kg; 3.94 mL/450 kg. IV dose: 0.18 mL/50 kg; 0.35 mL/100 kg; 0.88 mL/250 kg; 1.58 mL/450 kg. With these doses, moderate analgesia and muscle relaxation are obtained. The animal will remain standing in most cases; however, recumbency may occur. Suitable for general usage.
Deep sedation. IM dose: 0.88 mL/50 kg; 1.75 mL/100 kg; 4.68 mL/250 kg; 7.88 mL/450 kg. IV dose: 0.38 mL/50 kg; 0.75 mL/100 kg; 1.88 mL/250 kg; 3.38 mL/450 kg. With these doses, heavy analgesia and muscle relaxation will occur, causing recumbency. Suitable for major surgery such as claw amputation, caesarean section, eye ablation etc. in conjunction with appropriate local anaesthesia, as well as physical restraint of fractious animals.
Sheep, goats. 0.01 to 0.22 mg/kg bodyweight (0.01 to 0.22 mL/20 kg bodyweight) by intramuscular injection.
Dogs, cats. ? 23 kg bodyweight. 0.5 to 1.0 mg/kg bodyweight (0.25 to 0.5 mL/10 kg) by slow intravenous injection; 1.0 to 2.2 mg/kg bodyweight (0.5 to 1.1 mL/10 kg) by intramuscular or subcutaneous injection. Dogs ? 23 kg bodyweight. 1.1 mg/kg bodyweight (1.1 mL/20 kg) by intramuscular injection. The actions of Xylaxil-20 make it an excellent sedative for use in dogs and cats, producing a sleep-like state that lasts for 1 to 2 hours depending on the dosage used. It is useful as a premedicant to eliminate muscular hypertonic effects in cats during ketamine anaesthesia. Analgesia is not as profound as in cattle.
Vomiting will occur in most cases if there is food in the stomach.
For further detail on dosage, refer to literature with product or contact manufacturer.
Use in animals in the last month of pregnancy; it may precipitate an early parturition or abortion. Intra-arterial administration. Dogs or cats in conditions where emesis is undesirable, e.g. gastric dilatation and torsion, ingestion of caustic liquid or sharp foreign objects.