Ilium Methocarbamol

Injection

Actions
3-2(-methoxyphenoxy)-1,2-propanediol 1-carbamate

Methocarbamol is a guaifenesin carbamate which produces muscular relaxation by decreasing transmission in spinal and supraspinal polysynaptic pathways. The administration of methocarbamol to the target species reduces skeletal muscle hyperactivity without alteration of normal muscle tone.

When administered intravenously, methocarbamol has a dose-dependent long-acting effect that is essentially non-toxic. Methocarbamol has demonstrated efficacy in the control of a wide range of disorders involving acute muscle spasm.

This formulation is based on the monograph for a Methocarbamol Injection detailed in the United States Pharmacopoeia. Active constituent and excipients are tested to pharmacopoeial standards.

Indications

Dogs and Cats
Ilium Methocarbamol Injection is indicated as an adjunct therapy of acute inflammatory and traumatic conditions of the skeletal muscle and to reduce muscular spasms.
Efficacy of methocarbamol in the treatment of acute skeletal muscle hyperactivity secondary to the following conditions has been reported.

1.    Intervertebral disc syndrome, compressive myelitis, spinal cord injury where cord remains intact
2.    Trauma causing muscular and ligamentous sprains and strains
3.    Myositis, fibrositis, bursitis and synovitis
4.    Muscular spasm prior to or following surgical procedures
5.    Strychine Poisoning Ilium Methocarbamol promptly controls the classical and severe symptoms of strychnine poisoning
6.    Maintenance of muscle relaxation in tetanus
7.    Permethrin exposure
8.    Organophosphate toxicity

Horses
Ilium Methocarbamol Injection is indicated as an adjunct therapy of acute inflammatory and traumatic conditions of the skeletal muscle and to reduce muscular spasms, and effect striated muscle relaxation. Efficacy of methocarbamol in the treatment of acute muscle hyperactivity secondary to the following conditions has been reported.

1.    Trauma, muscular and ligamentous sprains and strains
2.    Myositis, fibrositis, bursitis and synovitis
3.    Tying up syndrome
4.    Muscular spasm prior to or following surgical procedures
5.    Maintenance of muscle relaxation in tetanus

Directions for use
Use the contents of this vial within 24 hours of initial broaching. Discard the unused portion.

Dosage should be based on the severity of the symptoms and resultant therapeutic response.Do not exceed a daily total of 330mg/kg bw.

Cats and Dogs: Administer by slow i.v. at a rate of 2mL per minute. Administer half dose, pause until animal relaxes then continue administration to effect.
Moderate conditions 44mg/kg bw
Sever conditions 55-220mg/kg bw

Horses: Intravenous injection only. Dose to effect. In horses the most effective response is achieved by injecting rapidly through a 15 or 17 gauge needle.

Moderate Conditions 4.4-22mg/kg bw
Severe conditions 22-55mg/kg bw

Presentation
Injection 20/100mL.

Composition
100mg/mL Methocarbamol

Contraindications
Methocarbamol is contraindicated in animals that are hypersensitive to the ingredients. CONTRAINDICATED for use in pregnant or lactating animals. CONTRAINDICATED for use in animals with known or suspected renal pathology.

Withholding period
Meat: NOT TO BE USED in horses intended for human consumption.

First Aid
If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131126

Storage
Store below 25°C (Air conditioning).

Registration
This product is not registered and is only available under APVMA Permit to a registered Veterinarian.